Piracetam

  • 800 mg Plus • $29.99 $18.99
  • Cognitive Enhancer
  • Dietary Supplement
  • 60 Vegetarian Capsules

 

What is Piracetam™?

Piracetam is a cyclic GABA derivative also known as 2-oxo-pyrrolidine acetamide. It is a dietary supplement that supports and enhances normal brain structure and function. Piracetam is considered an intelligence booster and central nervous system (CNS) stimulator with no known toxic or addictive capacity. The ability of Piracetam to "wake up your brain" is so impressive that it prompted researchers to define a new nutraceutical category called "nootropics" – nutrients for the mind.

Piracetam is similar in molecular structure to the amino acid pyroglutamate. They have the same basic chemical structure, 2-oxo-pyrrolidine, but they differ in their side chains. Pyroglutamate is 2-oxo-pyrrolidine carboxylic acid, and Piracetam is 2-oxo-pyrrolidine acetamide. Piracetam enhances cognition under conditions of hypoxia (too little oxygen), and also enhances memory and some kinds of learning in normal humans. Piracetam is used to nutritionally support beneficial therapeutic outcomes regarding alcoholism, stroke, Down syndrome, vertigo, Alzheimer's, dementia, sickle cell anemia, dyslexia, autism and other health problems (Pelton, 1989).

An intriguing effect of Piracetam is its promotion of the normal flow of information between the right and left hemispheres of the brain via the corpus callosum (Buresova, 1976). Communication between the two sides of the brain is associated with flashes of creativity. This may also be the basis for Piracetam's usefulness in nutritional support for beneficial therapeutic outcomes with dyslexia (Dilanni, 1985). Piracetam is thought to regulate cell membrane permeability more efficiently.

The effect of Piracetam can be enhanced if taken with many other nootropics, however it is recommended that lower servings of each be taken in conjunction with one another. When the nutrient choline and Piracetam are taken together there is a synergistic effect that causes a greater improvement in memory than the sum of each when taken alone (Bartus, 1981). Choline helps to replenish the important neurotransmitter acetylcholine which is metabolized with Piracetam.

One study suggests that Piracetam may regulate the number of cholinergic receptors in the brain. Older mice were given Piracetam for two weeks and then the density of muscarinic cholinergic receptors in their frontal cortexes was measured -- these older mice had 30-40% higher density of these receptors (Pilch, 1988). Piracetam appears to have a regenerative nourishing effect on the nervous system.

Piracetam has become popular as a cognitive enhancer among students. A two week regimen of Piracetam was found to enhance verbal memory in healthy college students.

Piracetam appears to regulate levels of lipofuscin in the brain. (Lipofuscin accumulation is a common symptom of aging and alcoholism).

Piracetam appears to be helpful in stimulating and regulating normal cognition in Alzheimers disease and senile dementia patients.

Piracetam has been found to support normal cognition after stroke. It also supports normal cognition in cases of chronic ischemia.

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Think clearer, remember more and feel better.

Suggested Serving: One (1) to six (6) capsules daily as a dietary supplement. Best when taken in intervals throughout the day. Greatest effect is seen generally after 3 weeks of daily use. Some literature recommends a high "attack" serving be taken for the first two days. When people first take Piracetam they may not notice any effect until they take a higher serving. After, a user may notice that a lower amount is sufficient. Piracetam takes effect within 30 to 60 minutes. Greatest effect is seen generally after 3 weeks of daily use..

Notice:

Individual results may vary. You should always consult with your physician before starting this product or any health-related program. Galantamine is currently not recommended for use by young individuals.

Precautions:

When taken with other brain enhancement products the individual doses may have to be reduced in order to avoid possible, although rare, mild effects such as headaches and nausea. If taken too late in the day, sleep delay may occur. Do not use if tamper resistant seal is missing or broken. Consult your physician prior to use if you are pregnant or nursing.

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DISCLAIMER

THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THESE PRODUCTS ARE NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE. ALL INFORMATION FOR ALL PRODUCTS IS EDUCATIONAL ONLY AND IS TAKEN FROM VARIOUS THIRD PARTY SOURCES, AVAILABLE ON REQUEST. IT DOES NOT AND SHOULD NOT REPLACE THE ADVICE OF YOUR PHYSICIAN. THESE PRODUCTS ARE OFFERED AS DIETARY SUPPLEMENTS ONLY. WE DO NOT ENDORSE OR ADOPT THE INFORMATION AND CLAIMS CONTAINED IN THE THIRD PARTY SOURCES.

Links:

Indicators of neuroprotection with galantamine.
Brain Res Bull. 2005 Jan 30;64(6):519-24. Geerts H.
In Silico Biosciences, 686 Westwind Drive, Berwyn, PA http://www.ncbi.nlm.nih.gov/pubmed/15639548

Galantamine for Alzheimer's disease.
Cochrane Database Syst Rev. 2004 Oct 18(4)
http://www.ncbi.nlm.nih.gov/pubmed/12137632?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Long-term outcomes of galantamine treatment in patients with Alzheimer disease.
Am J Geriatr Psychiatry. 2004 Sep-Oct;12(5):473-82.
http://www.ncbi.nlm.nih.gov/pubmed/15353385

Galantamine from snowdrop--the development of a modern drug against Alzheimer's disease from local Caucasian knowledge.
J Ethnopharmacol. 2004 Jun;92(2-3):147-62.
http://www.ncbi.nlm.nih.gov/pubmed/15137996

Clinical pharmacokinetics of galantamine.
Farlow MR. Indiana University School of Medicine, Indianapolis, Indiana
Clin Pharmacokinet. 2003;42(15):1383-92.
http://www.ncbi.nlm.nih.gov/pubmed/14674789

The cognitive benefits of galantamine are sustained for at least 36 months: a long-term extension trial.
Raskind MA. University of Washington School of Medicine Seattle 98108, USA.
Arch Neurol. 2004 Feb;61(2):252-6.
http://www.ncbi.nlm.nih.gov/pubmed/14967774

Effect of galantamine hydrobromide in chronic fatigue syndrome: a randomized controlled trial.
JAMA. 2004 Sep 8;292(10):1195-204.
http://www.ncbi.nlm.nih.gov/pubmed/15353532

http://www.ncbi.nlm.nih.gov/pubmed/11110737?dopt=Abstract

http://www.ncbi.nlm.nih.gov/pubmed/16809811?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=4&log$=relatedreviews&logdbfrom=pubmed

 

http://www.ncbi.nlm.nih.gov/pubmed/19032118?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

 

http://www.ncbi.nlm.nih.gov/pubmed/18949462?ordinalpos=17&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Galantamine: Preserving Memory and Cognitive Function  by Jim English http://www.nutritionreview.org/library/galantamine.html